International cooperation against the world drug problem A/RES/70/182 21. Urges Member States, where appropriate, to develop national responses to address the issue of drug-affected driving by, inter alia, exchanging information and best practices on effective responses, including through engagement with the international scientific and legal communities; 22. Notes with concern that the availability and accessibility of internationally controlled drugs for medical and scientific purposes, particularly for the relief of pain and for palliative care, remains low to non -existent in many countries of the world, and highlights the need for Member States, the Commission on Narcotic Drugs and the International Narcotics Control Board, in cooperation with the United Nations Office on Drugs and Crime and the World Health Organization, as appropriate, to address that situation by promoting measures to ensure their availability and accessibility for medical and scientif ic purposes, in accordance with national legislation, while simultaneously preventing their diversion, abuse and trafficking, in order to realize the aims of the three international drug control conventions and other relevant international instruments; 23. Urges all Member States to enact comprehensive measures aimed at stemming the abuse of prescription drugs, in particular through the establishment of awareness-raising initiatives targeting the general public and health-care providers; 24. Acknowledges the continuing efforts made and the progress achieved in countering the world drug problem, notes with great concern the continuing illicit production of and trafficking in opiates, the continuing illicit manufacture of and trafficking in cocaine, the increasing illicit production of and trafficking in cannabis, the ongoing global spread of the illicit manufacture of amphetamine -type stimulants and the increasing diversion of precursors, as well as the related distribution and use of illicit drugs, and stresses the need to strengthen and intensify joint efforts at the national, regional and international levels to tackle those global challenges in a more comprehensive manner, in accordance with the principle of common and shared responsibility, including by means of enhanced and bettercoordinated technical and financial assistance; 25. Expresses its concern that, despite all the efforts of Member States and the international community, there has been little change in the overall global situation regarding the production, use and health consequences of illicit drugs, as reflected in the World Drug Report 2015 of the United Nations Office on Drugs and Crime, and that further efforts are required from Member States and the international community; 26. Stresses that it is absolutely imperative for Member States to strengthen international efforts in order to achieve more effective results in addressing the world drug problem, including in the health, social, human rights, economic, justice and security fields; 27. Recognizes that it is necessary for Member States, under the three international drug control conventions and the fundamental principles of their domestic legal systems and national legislation, to consider, where appropriate: (a) Regularly reviewing and assessing their drug control policies, ensuring that they are effective, comprehensive, balanced and aimed at promoting the health and well-being of individuals, families, communities and society as a whole; (b) Providing, as appropriate, comprehensive, integrated drug demand reduction programmes, based on scientific evidence and covering a range of measures, including primary prevention, early intervention, treatment, care, rehabilitation, social reintegration and measures aimed at minimizing the negative 9/16