A/RES/65/59 world without nuclear weapons, in accordance with the objectives of the Treaty on the Non-Proliferation of Nuclear Weapons;3 1H 3. Further welcomes the expression by the 2010 Review Conference of deep concern at the catastrophic humanitarian consequences of any use of nuclear weapons, and its reaffirmation of the need for all States at all times to comply with applicable international law, including international humanitarian law; Welcomes the call by the 2010 Review Conference for the nuclear4. weapon States to further enhance transparency so as to increase mutual confidence, acknowledges recent positive steps in this regard, and calls upon all nuclear-weapon States to undertake activities in this regard at an early date; Also welcomes the reaffirmation of the continued validity of the practical 5. steps agreed to in the final document of the 2000 Review Conference of the Parties to the Treaty on the Non-Proliferation of Nuclear Weapons, 2 including the specific reaffirmation of the unequivocal undertaking of the nuclear-weapon States to accomplish the total elimination of their nuclear arsenals leading to nuclear disarmament, to which all States parties are committed under article VI of the Treaty; 2H Stresses the importance of the commitment made by the nuclear-weapon 6. States at the 2010 Review Conference to accelerate concrete progress on the steps leading to nuclear disarmament contained in the final document of the 2000 Review Conference, and of their prompt engagement with a view to ensuring substantial progress in advance of the 2014 session of the Preparatory Committee for the 2015 Review Conference of the Parties to the Treaty on the Non-Proliferation of Nuclear Weapons, and encourages the nuclear-weapon States to report regularly on the implementation of their commitments under the action plan on nuclear disarmament adopted by the 2010 Review Conference; Notes with satisfaction the commitment of the nuclear-weapon States to 7. undertake further efforts to reduce and ultimately eliminate all types of nuclear weapons, deployed and non-deployed, including through unilateral, bilateral, regional and multilateral measures; Encourages further steps by all nuclear-weapon States, in accordance 8. with the action plan on nuclear disarmament of the final document of the 2010 Review Conference, to ensure the irreversible removal of all fissile material designated by each nuclear-weapon State as no longer required for military purposes, and to support the development of appropriate verification capabilities relating to nuclear disarmament; Calls upon all States parties to the Treaty on the Non-Proliferation of 9. Nuclear Weapons to work towards the full implementation of the resolution on the Middle East adopted at the 1995 Review and Extension Conference of the Parties to the Treaty on the Non-Proliferation of Nuclear Weapons,1 and also calls upon the Secretary-General and the co-sponsors of the 1995 resolution, as well as all other relevant States and organizations, to undertake all necessary preparations to implement the practical steps agreed upon at the 2010 Review Conference in this regard; 3H 10. Continues to emphasize the central role of the Treaty on the Non-Proliferation of Nuclear Weapons and its universality in achieving nuclear disarmament and nuclear non-proliferation, and calls upon all States parties to respect their obligations; 3