A/RES/64/79 Member States to implement the Global Malaria Action Plan and meet the internationally agreed goals, including the Millennium Development Goals; 19. Expresses its concern about the increase in resistant strains of malaria in several regions of the world, and calls upon Member States, with support from the World Health Organization and other partners, to strengthen surveillance systems for drug and insecticide resistance and upon the World Health Organization to coordinate a global network for the monitoring of drug and insecticide resistance and to ensure that drug and insecticide testing is fully operational in order to enhance the use of current insecticide- and artemisinin-based combination therapies; 20. Urges all Member States experiencing resistance to conventional monotherapies to replace them with combination therapies, as recommended by the World Health Organization, and to develop the necessary financial, legislative and regulatory mechanisms in order to introduce artemisinin combination therapies at affordable prices and to prohibit the marketing of oral artemisinin monotherapies, in a timely manner; 21. Recognizes the importance of the development of safe and cost-effective vaccines and new medicines to prevent and treat malaria and the need for further and accelerated research, including into safe, effective and high-quality traditional therapies, using rigorous standards, including by providing support to the Special Programme for Research and Training in Tropical Diseases 9 and through effective global partnerships, such as the various malaria vaccine initiatives and the Medicines for Malaria Venture, where necessary stimulated by new incentives to secure their development and through effective and timely support towards pre-qualification of new antimalarials and their combinations; 8F 22. Calls upon the international community, including through existing partnerships, to increase investment in and efforts towards the research and development of new, safe and affordable malaria-related medicines, products and technologies, such as vaccines, rapid diagnostic tests, insecticides and delivery modes, to prevent and treat malaria, especially for at-risk children and pregnant women, in order to enhance effectiveness and delay the onset of resistance; 23. Calls upon malaria-endemic countries to assure favourable conditions for research institutions, including allocation of adequate resources and development of national policies and legal frameworks, where appropriate, with a view to, inter alia, informing policy formulation and strategic interventions on malaria; 24. Reaffirms the right to use, to the fullest extent, the provisions contained in the World Trade Organization Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS Agreement), 10 the Doha Declaration on the TRIPS Agreement and Public Health, 11 the decision of the World Trade Organization’s General Council of 30 August 2003 12 and amendments to article 31 of the Agreement, 13 which provide flexibilities for the protection of public health, and in particular to promote access to medicines for all, including the production, 9F 10F 1F 12F _______________ 9 A joint programme of the United Nations Children’s Fund, the United Nations Development Programme, the World Bank and the World Health Organization. 10 See Legal Instruments Embodying the Results of the Uruguay Round of Multilateral Trade Negotiations, done at Marrakesh on 15 April 1994 (GATT secretariat publication, Sales No. GATT/1994–7). 11 World Trade Organization, document WT/MIN(01)/DEC/2. Available from http://docsonline.wto.org. 12 See World Trade Organization, document WT/L/540 and Corr.1. Available from http://docsonline.wto.org. 13 See World Trade Organization, document WT/L/641. Available from http://docsonline.wto.org. 5