E/2014/27 E/CN.6/2014/15 in child-headed households, particularly girls, receive the support they need to ensure their continued attendance in school; 14. Urges Governments and other relevant stakeholders to address the situation faced by children and young persons, especially girls, who may be forced into child labour, including the worst forms of child labour, as a result of death or illness of family members or caregivers, and to protect these children and young persons from violence, including gender-based violence, sexual abuse, sexual exploitation, including commercial sexual exploitation, trafficking and labour exploitation; 15. Also urges Governments to take measures to integrate, inter alia, family and community-based approaches in policies and programmes aimed at providing prevention, treatment, care and support to women and girls living with or affected by HIV and AIDS; 16. Further urges Governments to ensure, in the context of prevention programmes for HIV and other sexually transmitted infections, accessible and affordable procurement of safe and effective prevention commodities, including male and female condoms, post-exposure prophylaxis and, where applicable, pre-exposure prophylaxis, to ensure that their supply is adequate and secure, and to promote ongoing research, including that for safe and effective microbicides; 17. Urges Governments: (a) To commit to remove before 2015, where feasible, obstacles that limit the capacity of low- and middle-income countries to provide affordable and effective HIV prevention and treatment products, diagnostics, medicines and commodities and other pharmaceutical products, as well as treatment for opportunistic infections and co-infections, and to reduce costs associated with life-long chronic care, including by amending national laws and regulations, as deemed appropriate by respective Governments, so as to optimize the use, to the full, of existing flexibilities under the World Trade Organization Agreement on Trade-Related Aspects of Intellectual Property Rights (TRIPS Agreement) specifically geared to promoting access to and trade in medicines, and, while recognizing the importance of the intellectual property rights regime in contributing to a more effective AIDS response, ensure that intellectual property rights provisions in trade agreements do not undermine these existing flexibilities, as confirmed in the Doha Declaration on the TRIPS Agreement and Public Health, and call for early acceptance of the amendment to article 31 of the TRIPS Agreement adopted by the General Council of the World Trade Organization in its decision of 6 December 2005; (b) To address barriers, regulations, policies and practices that prevent access to affordable HIV treatment by promoting generic competition in order to help reduce costs associated with life-long chronic care and by encouraging all States to apply measures and procedures for enforcing intellectual property rights in such a manner as to avoid creating barriers to the legitimate trade in medicines, and to provide for safeguards against the abuse of such measures and procedures; (c) To encourage the voluntary use, where appropriate, of new mechanisms such as partnerships, tiered pricing, open-source sharing of 14-02869 45/95