Central among women's and girls' health needs are those relating to their reproductive and sexual health. Substantive equality requires that States attend to the risk factors that predominantly affect women. For instance, since only women can become pregnant, a lack of access to contraceptives is bound to affect their health disproportionately. Equality in reproductive health requires access, without discrimination, to affordable, quality contraception; maternal health care, including during childbirth and the post-partum period; access to safe termination of pregnancy; access to effective screening and early treatment for breast and cervical cancer; and special attention to the high rate of HIV infections among young women and treatment to prevent mother-to-infant transmission.